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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c4e7edc45f3c515b11869486283ecd441b418ed6e338c6558cdd07dfba3225' 
  AND token = 'HlQ9fsBX3dgPv5pZQR3kvksWGF8urULe0DP1FMe/sTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}