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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0a0f00933483d5f4add28f3ee8f93fdddfa7229421f0717d67c1853a572889' 
  AND token = 'aQcgfnFL4OK97oUQ/Zfi42zCISpsz4VM2p0K5UgZHxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}