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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d1df49dbc2a47e3fea164b76e4512865c289aa0b28aab966344ae1f31158845' 
  AND token = 'A9izZH2TP36IFEFzrgyCCFdvFav6wZrjGKQh63eVEAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}