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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2516a00a9bcda346c877f3cee33d8804a443445f7125e89ed2a0b76129ada1' 
  AND token = 'AF58Z8IdkwBlaX/wyvXCIyTNzRi02oxY+MF2gFW4EdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}