SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d680488e35f6e88236a63740b177a41aca7544add83e4acdc3ffd23dfec21aa' 
  AND token = 'XNtW+JpbdMYvwFchTE8SQwUw5yamE39hyYb4sst3Ghk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}