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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d9daadc598e4c6f76fd61dd7216fdd3f9e00b3678fe6d74f7b0b866f4a6546' 
  AND token = 'IG0xnjolpGoxqaO55liT8CvDyCHX90FupREPaEUtC1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}