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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f81a04a564e493d8003ff3d7e556bf6160aa9850533e13fa95f4fb92ab5ab7' 
  AND token = 'G46Ju416ibogIdXG+6aUfU1PuZ6emvjQ7N3T34LliGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}