SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f4ad9ef727c69925666af352f7b11008ec7d9377dc38dd9e1fd3bd1e5bc939' 
  AND token = 'rcX6JAuDnVoROiFv0OoDvkHVW+3s5KHOcDklO+BtA8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}