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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97c29e1ebfec164d7925f0c67f7fad5dbbfca85abfcb9df2016d0a6551ef40b8' 
  AND token = 'mscOkpU1Qd69W9lF+qwQ1Npj6KtSAE2nP3c/4vuD72Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}