SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944e344aaf3f6923b0dbfc7eda2576e0aaf1aaefd9b85bf251f21be0e145795a' 
  AND token = 'EDwzAaLTn0s9eWB/HP8JGakTkZk8EqYUWjgAL+awAEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}