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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '454c1db13160d9c5b28bcc93745f76cee68c89e31b9fd606ff5075584fe60659' 
  AND token = 'DqsUDc/n/a6YcgLt1DiYbGwXAKXdjl6B03IlwXabiuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}