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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c410d7762775cb4c87476bbf50976bbd1ac2c6c2fd171f10828fb2bfcee7c546' 
  AND token = 'ilhvc472a9gWvx2ThtB85GFYFlVlfBaPJzh2rVwHg5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}