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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446f6a1aef862ac48d7ee3c65ea0cecc73dec693870f9ff2d0303bb4f17ae872' 
  AND token = 'NsHLlfS1XG1bEmL2UEOSDAKABNR6nQbBAUp5Ms/7V+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}