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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed0b93bd19f0c3e10f1f0133a90c9f37e53286dc35b188db77f671cf516a250' 
  AND token = 'sb5dNGAoFPsk4Sa7NoL0o4pDP+xcboHy4+VcBJpynVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}