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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c677db7e2e2dccb9817322b58ea4cdd926ca437bfbdd8c827f7afb891db2805f' 
  AND token = 'iPYHWhHzNBnEgPK0vf9PJQnjVpz5Hp0bkrk99b/gdhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}