SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e561a6c22d1a80a960e5110422b83279853a4c646a5edf8963ba16d15abacf1' 
  AND token = '0tho532Tk19guzvb32GrcAhUFEAsk25KsW3kKfjOSRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}