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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de0f701f873c36d79d45f2bca9d9f3b7b8b24a387fae4ba2bf5c4893e331bc7' 
  AND token = 'ml9C5rs3PzZ6Ie0z6gEAdC+9+suxYxQSsE77NCQgRZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}