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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8018863e5451ddfb8bcf1722eed2b4741076268d3919a6d52057f4e13ebdee9e' 
  AND token = 'GvhRLAvbrVj3OW39bBTAQMoP1KBea+pn5Z0bR2TLlbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}