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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517b33f81a191c0bef2465198f1c6d03b7ef30b72a75febc6c25aba1aa23bba8' 
  AND token = 'Eh4RzyAyTN6uQOqAS/IZXofDgBW1a6LeR+P2cUIrOuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}