SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca9d693315b30c47250835c56f73fd54c5c68e7629188b4895f0986680d77e7' 
  AND token = 'Z5wQT/mcJI3nz2Ttlahii7lM2ywOFSHyEfdC7QCBDO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}