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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5f2da35da7a2b1ea9f4df560ed3c9df07f7d6ac58f6259e89dfd98b236d793' 
  AND token = 'tSF4kzrb53XktqAsKy+0H4jv4TRAdWWdKV+HWVxMJww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}