SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0c71f35fed4b580ad1c14782020b0646826a63422c622e4630c934225a2702' 
  AND token = 'bflJ7xsm0g+V7XeZlpQgdnxwLrjzi/O3LareFELz+1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}