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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6563aaa02d86fc6511a2e04a2d097070420ece1e1fa7933908989b91a4f594b' 
  AND token = '+iZOa14Z7myTIRUSM661eX0wpkjeCPSPKpttN5th1QA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}