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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00e7fdf8fdb2289a84dbf2b5df435f9d77fb81c02bdf9272a448b8a680fc80e4' 
  AND token = 'GIKJilfnsO1ZwdGx1dYmjA2jmLMR+zb1Vroo7It25vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}