SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133b20fa5bac9d331e5252fcb545528d287e104f8ff805d123f54ef9d055661b' 
  AND token = 'ps+8l2uo+Vhngv8xc0LnTw70QIXO87+0b2VodQamkCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}