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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c871d8cd7778f260719ff912910b1075985897bee1da6b21f3d7e3a40e5c7c1a' 
  AND token = 'NxW2b2u66gJrDvCMWO9mrDn/Y1nB8YNK1nYY1mKcomU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}