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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7e4768dbf2ff25ae33ce8abe657062584c77f7b40b4b3897480904a21f5e64' 
  AND token = 'tNx+i45g01UP0V2GXgGUve3URn+ePr1t/Lubc40ZvJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}