SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd9915c7f0483368ab01024cf8f325fb03fdeee9d16d3b7a7d7feb40bf973dab' 
  AND token = 'aXfi2qpuAsdikdabESS8aGQZJFxHRH5RDEcXDOaJ8VA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}