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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6731a0ee06b5128bd11c8932055c532afea6abea575615778b182ede2745d96' 
  AND token = '+sW/6tHhQNYDpStX5gx7V+6+cGVYDbgMS0Mk56nY+OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}