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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121f157ef53c62fbbc82e181c0442312caa18dd3ca852e1daeacfe22ca65fa05' 
  AND token = 'JBsRcr6mdvipuxfCfvgshlzqdY2y/23Avz/6oPzOnJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}