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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37bfb1d052addb7503534126b14b3ba85f5f1679cbb200216d979622c670e8e4' 
  AND token = 'JHHZQpCRcdbuZwFfv2k1UhQHI3C19NsuZJvvvoblkdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}