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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528073b7bef43dc6e34242cd2834dd618940fa7b23c41f4c0e1fdd59f61d1873' 
  AND token = '5DpWbfFiy+S78ggxTX9DU0PEBcQY5m2mOaeUGoOnBX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}