SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee3b3b79114e45bc83ecb0a0320fccfc5c13c05469032067c09392941e6993f' 
  AND token = 'vN4v9uj2wdnSW0fc9/HI4WnDu1/N5BflgkmDjpmLYXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}