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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '476e46a18a1ca3d410e75aaee4e85bf7d238dc2b99472e61292841580793943a' 
  AND token = 'dUabOsVSY1xT1ss9D/zTmnKGB7JD1y0w0GH9TCS/FHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}