SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e1ea692f63a2ec2524974370290d803743539f377b005b0b7194a750d10ade' 
  AND token = 'sRTXTRUGrQM3NmjidiLX17HzQY19lvtVfLH2y/DvYAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}