SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffcbdc7e2eae06191c8c1936a9c662829f82c6f35cecdba4456728b30129e65' 
  AND token = 'eoPl4fSpqCBzjqC6t3xooFbfVXBkp/NwA7Uyh/2M1cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}