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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e28fa1e070cb9dbd58376552ca28fbf8c993c0189b31e59e32afff402e5478' 
  AND token = 'i98XT4UGjzvx5aGZVem8/09UBdlco50Ltcnkhe3dxMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}