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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df07bd0ae7b5410f24105acc59ada8881bcfc17e19074432c387274f48c0440a' 
  AND token = 'ijwlN8t1S8Z3JiKvVYEuNUEX9u3kcHKNFFWmuhnxyiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}