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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded5d15d277b4488bb22e9ddcfed7b34940992b0b143fbf62457e7b55e12f30d' 
  AND token = 'A9y5vkJ1FmHMam/Bd6QGHUh6EQP0EMQA12hvhmPuvXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}