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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75238ed1a7392744d3736afdcde5d6dc7260650789352b960dbbf1e5baca6740' 
  AND token = 'swjt9wxP9IwgpRg2SlVt6OK2LqRoOtzFNGxQwnWzS28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}