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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65fad0d387b0a4581fefa6c8b963512c9ff860691e89db2e4d8ca3293c752dc' 
  AND token = '2fxQMiU26Ieul66ztkZ/KSxHNbw7zIb8T42o1yyOHr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}