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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f290f5e651625149f08461a491f782419bc5979bfec91df13bbd5cfe4d5ee6b' 
  AND token = '4QSgYILwtgACcCJEfBTUjybrURhjTWfLeAuCbMZZRWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}