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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7588036cb91a0e316eed7cc2c1c3aab4903ebb2fa6b3ecb0efe5ccbfa838b6' 
  AND token = '7Rixz8Z2NxDUH/3BiOjH+g+jvkJ23KGwBhsWS2CVcQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}