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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ea041747d1b95b86cf29e13a7f2e64e76e7d423e360f97d1ecf8962f69503f' 
  AND token = '4jwvEHlEsthyJD7auZ3XRp11tAtw/oDJMQ1ufKxByf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}