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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4014c4b11a7c29477f67c46a6209e59b3a838b0c212ef10c37992059920667' 
  AND token = '1DbU583Zn3HV2KXS7abevfQwnfipFJl7+pAH0PmVirs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}