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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f5e7db0fe2fc2e8f63933b48a79bfd1ebdfce6057b7f8a22fe9627e3560edd4' 
  AND token = 'IV6mVc6Q9hzNYSg6t0MnbF9keE+35RCcd9HLtK9EAEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}