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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bbaf553c3c8f3cde83fc6a17f6769d55c0c6e673cde7fbf4e472b024c16a750' 
  AND token = 'I8I1QlQnu8qRx5Y1/z3d3PcLYUzH/e4qA53dzK5rIeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}