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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1d4d3030c65b52283f79abc833af354e73151ee9ed2eba2902ba12c143b307' 
  AND token = '3onk7l51azhxFYNj1K5zyfssxtVX1PgtwlLQ9UxVV6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}