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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5315314fb92198e42f824d5e2f4c970345a563add757846c4bc2102b6c81d8c0' 
  AND token = 'c2EePg2pmlF0N17xEwSNuF3/Rwes1RSa7wiuN6YGICo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}