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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0d446ba3cc301dfe420f37cba310b7455d32b2069fae9f669a29b5407cf91f' 
  AND token = 'IpAiUfRaERGa9lpweq9Ibc6QY+UO/LBpRe6I2w936Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}